Principles and Practice of Clinical Research


Globalization has contributed significantly to the dissemination of information in different areas of knowledge. Scientific papers are therefore the way to contribute to this global debate and advance in science. 

PPCR will therefore contribute to disseminate the latest research and updates on clinical research.

PPCR aims to providing a medium for the publication of scientific articles of high quality, thus promoting the work and training of clinical researchers globally. 

The journal is initially expected to be quarterly and will be open for new submissions from April 2015.

Send your scientific article!

Check out the rules for submission. As the journal aims to be an international publication, all information and article submission should be formatted in English.



Felipe Fregni, MD, PhD, MPH
Associate Professor of Neurology and PMR, Harvard Medical School
Director, Principles and Practice of Clinical Research, ECPE, Harvard T.H. Chan School of Public Health
Director, Spaulding Neuromodulation Center, Spaulding Rehabilitation Hospital, Harvard Medical School

Associate Editors

Sandra Carvalho, PhD & Jorge Leite, PhD
Laboratory of Neuromodulation, Spaulding Rehabilitation Hospital, Harvard Medical School
Neuropsychophysiology Lab, University of Minho

Managing Editors

Felipe Jones & Aurore Thibaut, PhD
Laboratory of Neuromodulation, Spaulding Rehabilitation Hospital, Harvard Medical School

Executive Editor

Rivadavio Amorim, DDS, MSc, PhD
University of Brasilia, Brasilia, Brazil



New online submission system


We are proud to announce that all new article submission will be processed by an online submission system.

Upon registry you will able to submit your manuscript by clicking on new submission on your user home. If new submission is not available please got to My Profile and make sure the author role is selected.

Make sure you upload all the files as explained in the instructions to authors. If you have any questions please contact us by email.

Posted: 2016-04-02
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Early Access

Table of Contents


Deniz Doruk, Ingrid Moreno-Duarte, Leon Morales-Quezada, Felipe Fregni


Óscar F Goncalves, Sandra Carvalho, Jorge Leite, Ana Fernandes-Gonçalves, Angel Carracedo, Adriana Sampaio

Study Design

Sherine Elsayed Mohamed Ismail, Maryam Khalil, Jani Hafez, Oyndamola Yusuf, Jane Thomson, Muhammed Siddiqui, K.H. Mujtaba Quadri
Franziska Schoeppe, Juçara Franca, Wilson Fandino, Adailson Siqueira, Alawiya Gadallah, Andrea Castillo Medina, Antoinette Blackman, Ejaz Nadeem, Fabiana Gonçalves, Hani Abdalla, Judith Sanchez Raya, Juliana Gonzalez, Odimary Silva, Paula Kataguiri, Paulo Henrique Rosado-de-Castro, Sandro Pereira, Regina Ruiz, Sol Calero, Lotfi B. Merabet